Pantosec-D Tablet: Uses, Side Effects, Composition & Dosages

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Pantosec-D tablet belongs to a class of dopamine antagonist (drug which blocks dopamine receptors) group of drugs. The medicine prevents the tendency of nausea and vomiting in patients suffering from problems related to the gastrointestinal tract such as gastric ulcer, small intestine ulcer, heartburn, etc. The medicine may also be prescribed as a combination of medicine with the drugs used for the treatment of Parkinson’s disease. The medicine is manufactured in India by Cipla.

Uses and Benifits of Pantosec-D Tablet:

Pantosec is usually prescribed for the treatment and prevention of the following diseases and conditions –

  • Gastric Ulcer
  • Nausea
  • Vomiting
  • Gastrin-secreting tumour
  • Small Intestine Ulcer
  • Heartburn
  • Esophageal Mucosal Injury
  • Gas in abdomen
  • Idiopathic or diabetic gastroparesis
  • Bloating

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Side Effects of Pantosec-D Tablet:

Some of the side effects associated with the consumption of Pantosec-D tablets are:

  • Pain in the breast
  • Blurred Vision
  • Whirling Sensation
  • Balance loss for sometime
  • Itching
  • The rise in Body Temperature
  • Bone Fracture risks
  • Dryness of Mouth
  • Irregularity in heartbeats
  • Menstrual Irregularities
  • Face or throat swelling
  • Discharge of milk from the nipples of a breastfeeding woman
  • Male breast swelling

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Common Dosage of Pantosec-D Tablet:

The generally prescribed dosage of Pantosec tablets is a 10 mg tablet to be taken once in a day. The dosage may be increased to 30 mg depending upon the condition of the patient.

  • Missed Dose : If a patient misses a dose of Pantosec-D tablets, it must be taken as soon as the patient remembers about it. However, if it is almost the time to consume the next dose, the previous dose must be skipped. Patients are advised not to consume two doses to compensate for the missed dose.
  • Overdose : Administering more than the prescribed dose of the medicine may lead to severe side effects such as drowsiness, convulsions, agitation. If an overdose is suspected, the patient must immediately visit a doctor.

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Composition and Nature of Pantosec-D Tablet:

The medicine belongs to a class of dopamine antagonists and comprises of two main ingredients namely domeperidone and pantoprazole.

  • Domperidone (10 MG) – It is a blocker of dopamine receptors. The medicine speeds up the peristalsis movement and leads to the release of prolactin.
  • Pantoprazole (40 MG) – The medicine is a proton pump inhibitor and is used to manage gastroesophageal reflux disease (GERD) and other gastrointestinal disorders.

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How Pantosec-D Tablet works?

The medicine attaches to the dopaminergic receptors and inhibits the release of dopamine. This action of medicine facilitates gastric emptying and aids in treating various gastrointestinal disorders. The medicine also works by tightening the muscles near the entrance of the stomach and relaxes the ones present at the exit. This action of this medicine aids to speed up the passing of food from the stomach to the intestine which eventually prevents vomiting and feeling of sickness.

Individual mechanism –

  • Domperidone – Domperidone acts as a peristaltic stimulant that increases the speed of the food to move to intestine from the stomach at a faster speed. The medicine lowers the pressure on esophageal sphincter thereby facilitating gastric emptying. The medicine also has antiemetic properties, Domperidone has a high affinity for D2 and D3 dopamine receptors which are found in the chemoreceptor trigger zone and regulate nausea and vomiting.
  • Pantoprazole – Pantoprazole binds to an enzyme which is implicated in accelerating the final step in the acid secretion pathway. This action of pantoprazole inhibits the secretion of gastric acid and reduces stomach acidity.

Precaution and Warning – When to Avoid Pantosec-D Tablet?

The following warnings and precautions must be kept in mind while administering Pantosec-D tablets –

  • The patients are advised to inform the doctor about any ongoing medicines or treatments.
  • Patients are advised not to drive or operate heavy machinery after immediately after the consumption of Pantosec-D tablet as it may induce excessive drowsiness in patients.
  • Patients suffering from liver-related ailments or deficiency of vitamin B12 must not consume Pantosec-D tablets as it may lead to severe side effects or worsening of the condition.
  • Patients suffering from cardiac arrhythmia must consult the doctor before administering Panstosec-D tablets, as medicine may interact with the disease and lead to worsening of the condition.
  • Patients allergic to the components of the medicine must avoid its consumption.
  • Patients suffering from conditions such as bradycardia, glucose or galactose malabsorption, hypokalaemia, hypomagnesaemia, hyperkalaemia, the renal impairment must exercise extra caution while administering the medicine. Such patients must consult the doctor before starting the consumption of medicine.
  • Children should not be given this medicine unless advised by a doctor.
  • Pregnant women must not consume this medicine unless the benefits outweigh the risks and the medicine is deemed absolutely necessary by a doctor. Self-medication must be avoided.
  • Breastfeeding women may not consume this medicine, as it may pass from the milk and cause harm to the baby. The medicine should only be administered if advised by a doctor.

Substitutes for Pantosec-D Tablet:

Following are the substitutes of Pantosec-D tablet

  • Piza-D Tablet manufactured by Unimarck Healthcare Ltd
  • Pentab-D Tablet manufactured by Alembic Pharmaceuticals Ltd
  • Lupipan DSR Tablet manufactured by Lupin Ltd
  • Pantozec D 10mg/40mg Tablet manufactured by Micro Labs Ltd
  • Gopan D 10 mg/40 mg Tablet manufactured by Gold Line
  • Pentowok D Tablet manufactured by Wockhardt Ltd
  • Peptilcer D 10mg/40mg Tablet manufactured by Biochem Pharmaceutical Industries
  • Panfirst D 10 mg/40 mg Tablet manufactured by Zyphar’s Pharmaceuticals Pvt Ltd
  • Panido-D Tablet manufactured by Shine Pharmaceuticals Ltd
  • Pentotas D 10 mg/40 mg Tablet manufactured by Intas Pharmaceuticals Ltd
  • Pop D 10mg/40mg Tablet manufactured by Winsome Laboratories Pvt Ltd
  • Pentalink L 10 mg/40 mg Tablet manufactured by Lincoln Pharmaceuticals Ltd
  • Inox 10 mg/40 mg Tablet manufactured by Thrift Pharmaceuticals
  • Anleo-D Tablet manufactured by AN Pharmaceuticals Pvt Ltd
  • Pave D Tablet manufactured by Biomax Biotechnics Pvt Ltd
  • Pentalink-D 10mg/40mg Tablet manufactured by Lincoln Pharmaceuticals Ltd
  • Prazo-D Tablet manufactured by Zaneka Healthcare Pvt Ltd
  • Pantova-D Tablet manufactured by Seagull Pharmaceutical Pvt Ltd
  • Aspan-D 10mg/40mg Tablet manufactured by Aspire Remedies
  • Unopan D Tablet manufactured by Shankus Acme Pharma Pvt Ltd
  • Pansec RX 10mg/40mg Tablet manufactured by Cipla Ltd
  • Zopen D 10 mg/40 mg Tablet manufactured by Kentreck Laboratories Pvt Ltd
  • Aldepraz D 10 mg/40 mg Tablet manufactured by Alde Medi Impex Ltd
  • Pantonis D Tablet manufactured by Adonis Laboratories Pvt Ltd
  • Maxipan 12 10mg/40mg Tablet manufactured by Widcure Healthcare
  • Rizole D Tablet manufactured by R B Pharmaceuticals
  • PZ 4D 10mg/40mg Tablet manufactured by National Chemical & Pharmaceuticals Works Pvt Ltd
  • Panila-D 10mg/40mg Tablet manufactured by Khlorophylls Biotech Pvt Ltd
  • Pancert-D Tablet manufactured by Sigmund Promedica
  • Pazole D 10 mg/40 mg Tablet manufactured by Admac Pharma Ltd

Pantosec-D Tablet Interactions with Other Drugs:

Interaction with medicines –

Following medicines may interact with Pantosec-D tablets –

  • Fluconazole
  • Fosamprenavir
  • Indinavir
  • Amprenavir
  • Antacids
  • Aprepitant
  • Atazanavir
  • Atropine
  • Saquinavir
  • Telithromycin
  • Verapamil
  • Voriconazole
  • Pantoprazole
  • Posaconazole
  • Ritonavir
  • Warfarin
  • Itraconazole
  • Itraconazole,
  • Ketoconazole
  • Methotrexate
  • Nefazodone
  • Nelfinavir
  • Amiodarone
  • Clarithromycin
  • Diltiazem
  • Erlotinib
  • Erythromycin

Interactions with Diseases

The medicine may interact with the following diseases –

  • A tumour in the pituitary gland – Pantosec-D tablets may cause severe side effects in patients having a tumour in the pituitary gland.
  • Heart-related ailments – patients suffering from heart-related ailments such as Congestive Heart failure are advised not to consume this medicine as it may worsen their condition.
  • Kidney Diseases- The patients suffering from kidney related ailments are advised not to consume this medicine as it may negatively affect the patient’s health.

Interaction with alcohol

The medicine should not be consumed alcohol as it may induce excessive drowsiness and dizziness in the patients.

Variants of Pantosec-D:

One variant of Pantosec-D tablet is –

  • New Pantosec D SR Capsule

Medicines that should not be taken with Pantosec-D tablets

Following medicines should not be consumed with Pantosec- D tablets –

  • Fluconazole
  • Fosamprenavir
  • Indinavir
  • Amprenavir
  • Antacids
  • Aprepitant
  • Atazanavir
  • Atropine
  • Saquinavir
  • Telithromycin
  • Verapamil
  • Voriconazole
  • Pantoprazole
  • Posaconazole
  • Ritonavir
  • Warfarin
  • Itraconazole
  • Itraconazole,
  • Ketoconazole
  • Methotrexate
  • Nefazodone
  • Nelfinavir
  • Amiodarone
  • Clarithromycin
  • Diltiazem
  • Erlotinib
  • Erythromycin

How to store Pantosec-D?

Following are the storage instructions for Pantosec-D tablets –

  • The medicine must be stored in a cool and dry place.
  • The medicine must be stored away from direct heat and sunlight.
  • The medicine must be kept away from the reach of pets and children.

FAQs:

1) Is Pantosec-D safe to be consumed by pregnant women?

Ans: No. The medicine is not safe to be consumed by pregnant women. This is because the medicine poses a serious threat to the health of developing fetuses. The medicine may be consumed by pregnant women only if deemed absolutely necessary by a doctor.

2) Is it safe to drive or operate heavy machinery after consuming Pantosec-D tablets?

Ans: No. It is not safe to drive or operate heavy machinery after consuming Pantosec-D tablets. This is because the medicine induces dizziness and drowsiness in the patients after being administered.

3)  What will happen if I accidentally consume an expired dose of Pantosec-D Tablet?

Ans: Although it is always recommended to check the expiry date of the medicine before administering it, a single expired dose may not cause any severe side effects. It must be noted that the efficacy of the medicine may be affected as an expired tablet will not be as effective in treating the symptoms. In case of experiencing any severe side effects, a doctor must be consulted immediately to seek remedial action.

4)  Should I administer Pantosec-D Tablet before or after having a meal?

Ans: Pantosec-D must be consumed empty stomach for its better absorption and maximum efficacy. For case-specific recommendations, it is advised to consult a doctor before starting the dose of the medicine.

5) Is this medicine habit forming?

Ans: No. The medicine does have any habit-forming tendencies.

6) Can Pantosec-D be used to alleviate bloating?

Ans: Yes, Pantosec-D can be prescribed to alleviate bloating and the discomfort associated with it. The medicine belongs to a class of drugs known as dopamine antagonists which are used for the treatment of conditions such as gastrointestinal problems such as gastric ulcer, small intestine ulcer, heartburn, etc.

7) What will happen if I continuously forget to take Pantosec-D?

Ans: Missing a single dose of the medicine may not cause many effects. However, for medicine to work properly some concentration of medicine should always be present in the body. If a patient continuously misses the dose of the Pantosec-D, the medicine may not be able to completely cure the condition it has been prescribed for.

8) What will happen if overdose on Pantosec-D tablet?

Ans: Taking more than the recommended dose of the medicine may lead to side effects such as drowsiness, convulsions, agitation, etc. In case of a suspected overdose, it is advised to consult a doctor to seek remedial action.

9)  What are the common side effects associated with Pantosec-D Tablet?

Ans: The common side effects associated with Pantosec-D Tablet are –
Stomach pain
Dryness in mouth
Flatulence
Diarrhoea
Headache
Dizziness

10)  Is Pantosec-D Tablet available as an Over-the-Counter medicine?

Ans: Yes, Pantosec-D is available as an Over-the-counter medicine. The medicine is a dopamine antagonist which is used for the treatment of various gastrointestinal disorders.

11) Can I take Pantosec-D Tablet along with other antidepressants?

Ans: No, antidepressants are not recommended to be administered along with Pantosec-D Tablets as they may interact and lead to severe side effects when co-administered. A doctor must be consulted before starting the dose of any medicine to avoid the occurrence of drug interactions.

12) Can I immediately stop the consumption of this medicine as soon as I see improvement in my conditions?

Ans: No, it is not advisable to abruptly stop or alter the dosage of the medicine even if an improvement in the condition is experienced. Leaving the course of medicine in between may not completely cure the condition it has been prescribed for. The doctor must be consulted before stopping the consumption of the medicine as he may prescribe an alternate dose if side effects persist.

13) What is Pantosec-D Tablet used for?

Ans: Pantosec-D Tablet is used for the treatment and prevention of various conditions and diseases such as –
Acidity
Heartburn
Nausea and vomiting
Gastric motility disorders

14) Can administering Pantosec-D Tablet causes difficulty in breathing?

Ans: Yes, difficulty in breathing is a very common side effect associated with the use of Pantosec-D Tablets.  Patients are advised to visit a doctor if the pain persists for a prolonged duration.

15) Is Pantosec-D safe to be consumed by lactating mothers?

Ans: Yes. The medicine is safe to be consumed by lactating mothers. However, it is highly recommended that patients should administer medicine only if prescribed by a doctor.

16) What are the storage requirements for medicine?

Ans:
The medicine should be stored away from direct sunlight and heat.
It should be stored in a dry and cool place.
The medicine should be kept out of reach of pets and children

17) Is Pantosec-D banned in India?

Ans: Pantosec-D is an over-the-counter medicine that is readily available at all medical stores. It is not banned in India.

18)  Is Pantosec-D a prescription-only drug?

Ans: No, Pantosec-D is not a prescription-only drug. The medicine is generally used for the treatment of nausea, vomiting, and heartburn.   The medicine belongs to the category dopamine antagonist and can be purchased without a doctor’s prescription.

19) Do I need to avoid a particular food item while administering a dose of Pantosec-D Tablet?

Ans: No, you do not need to avoid a particular food item while administering a dose of Pantosec-D tablet. The medicine is not known to cause any interaction with the food items. However, your doctor may ask you to avoid certain products depending upon your condition.

20) What are the general precautions and warnings to be followed while taking Pantosec-D Tablet?

Ans:
The patients are advised to inform the doctor about any ongoing medicines or treatments.
Patients are advised not to drive or operate heavy machinery immediately after the consumption of Pantosec-D tablet as it may induce excessive drowsiness in patients.
Patients suffering from liver-related ailments or deficiency of vitamin B12 must not consume Pantosec-D tablets as it may lead to severe side effects or worsening of the condition.
Patients suffering from cardiac arrhythmia must consult the doctor before administering Panstosec-D tablets, as medicine may interact with the disease and lead to worsening of the condition.
Patients allergic to the components of the medicine must avoid its consumption.
Patients suffering from conditions such as bradycardia, glucose or galactose malabsorption, hypokalemia, hypomagnesemia, hyperkalemia, the renal impairment must exercise extra caution while administering the medicine. Such patients must consult the doctor before starting the consumption of medicine.
Children should not be given this medicine unless advised by a doctor.
Pregnant women must not consume this medicine unless the benefits outweigh the risks and the medicine is deemed absolutely necessary by a doctor. Self-medication must be avoided.
Breastfeeding women may not consume this medicine, as it may pass from the milk and cause harm to the baby. The medicine should only be administered if advised by a doctor.

21) What if I miss a single dose of Pantosec-D?

Ans: It is generally advised to take the missed dose as soon as possible. If it is almost time for the next scheduled dose, it is recommended to administer the next dose and not take the skipped dose. Under no circumstance should a double dose be taken to compensate for the missed dose as it may lead to drug toxicity or other side effects.

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