Pantop D SR Capsule belongs to a category of dopamine antagonists. The drug prevents the tendency of nausea and vomiting in patients suffering from problems related to the gastrointestinal tract or conditions like Parkinson’s disease.
Pantop D SR Capsule works by tightening the muscles at the beginning of the stomach and relaxing the ones present at the exit. This action of the medicine prevents the backflow of the food and speeds up the passing of food to the intestine.
Uses and Benefits of Pantop D SR:
Pantop D SR Capsule are used for the treatment of the following conditions and symptoms –
- Intestinal or stomach ulcers
- Idiopathic or diabetic gastroparesis
- Vomiting and intractable nausea
- Gastric problems
- Backflow of acid from the stomach
- Inflammation of the esophagus
- Heartburn
- Heavy bloating
Side Effects of Pantop D SR:
Regular consumption of medicine may cause some side effects in the patients. These side effects may range from being moderate to severe. Mentioned below are some of the side effects associated with the consumption of Pantop D SR Capsule:
- A headache
- Itching
- Diarrhea
- Feeling low
- Extrapyramidal symptoms
- Dryness of the mouth
- Constipation
- Increased risk of bone fractures
- Dizziness
- Rashes
- Enlargement of the breasts
- Tenderness in the breasts
- Galactorrhoea
- Amenorrhea
- Pain in the breasts
- Irregular menstruation
- Lactation disorder
- Excess of glucose in the blood
- Hyperlipidaemia
- Flu syndrome
- Blurred vision
Common Dosage of Pantop D SR:
Depending upon the age and condition of the patient a doctor may create a personalized dosage plan. The usual dose of Pantop D SR Capsule is 10 mg which may be taken 15-30 minutes prior to taking the meal. The maximum dose that may be prescribed for adults is 30 mg.
- Missed Dosage: In case the dose is missed, the patients must take Pantop D SR as soon as they remember. However, if it is already the time for the next dose, they must refrain from taking two doses at very short intervals. If the patients usually forget to take the medicine on time, they must set an alarm to remind them about taking the medicine.
- Overdose: Taking more than the prescribed dose of Pantop D SR may do more harm than good to the body. An overdose of the medicine may lead to severe side effects as well as drug toxicity. In case an overdose is suspected, the patients must immediately consult the doctor.
Composition & Nature of Pantop D SR:
The vomiting center of the brain is present in the brain’s fourth ventricle. An area called a chemoreceptor trigger zone (CTZ) or postrema is present in this ventricle. CTZ contains the receptors for dopamine and other neurotransmitters. When any of these receptors are stimulated, it may lead to vomiting.nPantop D SR is a dopamine antagonist i.e. it blocks the activation of this neurotransmitter by binding to its receptor sites.
The medicine is basically composed of two compounds namely domperidone and pantoprazole.
- Domperidone – It is a blocker of dopamine receptors and speeds the gastrointestinal peristalsis.
- Pantoprazole – It is a proton pump inhibitor drug which suppresses the gastric acid production in the stomach.
Pantop D SR Price in India:
- Aristo Pharmaceuticals Pvt Ltd (10 capsules): INR 115
How to use Pantop D SR Capsule?
For medicine to work efficiently it must be taken properly without skipping the doses. Here is how the patients must consume Pantop D SR Capsule –
- Pantop D SR must be taken as directed by the doctor.
- The medicine must be taken for duration mentioned in the prescription.
- Pantop D SR must be swallowed whole and not chewed, crushed or broken.
- The capsules must be taken empty stomach.
How Pantop D SR works?
The medicine attaches to the receptors of dopamine and inhibits its production. This action, in turn, decreases the bowel transit time and facilitates the gastric emptying.
- Mechanism of Domperidone – Domperidone blocks the dopamine receptors and speeds up the gastrointestinal peristalsis. It lowers the pressure on the esophageal sphincter thereby decreasing the small bowel transit time. Domperidone also blocks the activity of dopamine at the chemoreceptor trigger zone.
- Mechanism of Pantoprazole – Pantoprazole is a proton pump inhibitor which suppresses the final step in gastric acid production.
When Pantop D SR is prescribed?
Pantop D SR Capsule is a combination medicine. It is prescribed for the treatment of gastroesophageal reflux diseases as well as to prevent vomiting and reduce nausea. The medicine is usually prescribed to patients who do not respond well to pantoprazole alone.
Warnings/Precautions – When to avoid Pantop D SR Capsule?
- Patients with liver disease or vitamin B12 deficiency must consume Pantop D SR only after consulting a doctor.
- If after consuming Pantop D SR, a patient experiences symptoms of cardiac arrhythmia, the medicine must be immediately discontinued.
- The patients must refrain from consuming the medicine if they are allergic to any of its components.
- Pantop D SR must be administered with caution in the elderly.
- Patients having low magnesium levels must thoroughly consult their doctors before consuming the medicine.
- The drug must not be given to children.
- Pregnant women may not be prescribed Pantop D SR Capsule until absolutely necessary.
- The medicine may not be safe to be consumed by lactating mothers. However, the doctor may prescribe the medicine under certain conditions.
- Using the drug for prolonged durations may increase the risk of bone fractures. The risk is specifically higher for the elderly. To reduce the risk, the doctor may prescribe calcium and vitamin D supplements along with Pantop D SR.
- Consuming the medicine for a longer duration may decrease body’s efficiency to absorb vitamin B12. Therefore, if the patient is already suffering from a deficiency of vitamin B12 it must be foretold to the doctor.
- Pantop D SR may interact with other medicines leading to severe side effects. However, Pantop D SR may be prescribed if the benefits outweigh the risks.
- Patients with acute or long-term electrolyte imbalance must remain extra cautious while consuming the medicine. Regular monitoring of the electrolyte levels must be carried out in order to avoid worsening of the condition. Also, alternative treatment may be given along with Pantop D SR Capsule to circumvent the adverse side effects.
- Regular consumption of Pantop D SR Capsule may increase the risk of prolactin (hormone that causes breasts to grow and develop milk) imbalance in the body. This imbalance may disturb the menstrual cycle in women. In men, prolactin imbalance may lead to the growth of breasts.
- Patients suffering from kidney diseases must use medicine with extreme caution. Pantop D SR may have adverse side effects on the kidney. A close monitoring and regular dose adjustments may be needed in some clinical conditions.
Pantop D SR Interactions:
Drugs interact with other medicines, food items and beverages. These interactions may lower the efficacy of the drug and lead to adverse side effects. Mentioned below are some of the interactions exhibited by Pantop D SR Capsule.
Interaction with medicines
The drug may interact with following medicines –
- Cisapride
- Tramadol
- Warfarin
- Digoxin
- Ketoconazole
- Methotrexate
- Erythromycin
Interactions with diseases
- Liver Disease – Pantop D SR must be taken with caution in patients suffering from liver diseases. Regular consumption of the medicine may increase the risk of side effects. Close monitoring of the liver functions is required in patients suffering from liver diseases.
- Osteoporosis – Patients suffering from Osteoporosis must take Pantop D SR with caution as the consumption of Pantop D SR Capsule increases the risk of bone fractures. Regular dose adjustments may be required to ensure that the bones are not affected to a larger extent. Also, the doctor may prescribe calcium and vitamin supplements to reduce the risk.
- Kidney disease – Patients suffering from kidney disease may need regular monitoring of the renal function while consuming the medicine. This is so because; the regular consumption of medicine increases the risk of side effects. Also, the doctor may make dose adjustments to ensure that no side effects appear.
- Hypomagnesaemia – Prolonged consumption of Pantop D SR may lower the magnesium levels in the body. Therefore, patients suffering from hypomagnesaemia may require regular monitoring of magnesium levels in the body.
- Intestinal problems – Patients consuming Pantop D SR Capsule should remain extra cautious while using Pantop D SR. Regular intake of the medicine may worsen the conditions such as internal bleeding and perforation of the stomach and intestine.
Lab interactions
- Tetrahydrocannabinol (THC) – A patient may get a false positive result for Tetrahydrocannabinol (THC) test while on Pantop D SR Capsule. It is suggested that the patients must inform the doctor before undergoing the test. An alternative lab test may be performed to confirm the results of the THC test.
Substitutes for Pantop D SR:
Following medicines can be prescribed in case Pantop D SR Capsule are not available –
- Pan-D Capsule manufactured by Alkem Laboratories Ltd
- Pantakind-DSR Capsule manufactured by Mankind Pharma Ltd
- Pantodac DSR Capsule manufactured by Zydus Cadila
- Nupenta-DSR Capsule manufactured by Macleods Pharmaceuticals Pvt Ltd
- Pantadom-SR Capsule manufactured by Mankind Pharma Ltd
- Zipant D SR Capsule manufactured by FDC Ltd
- Pantium DSR Capsule manufactured by Intas Pharmaceuticals Ltd
- P2i-D Capsule SR manufactured by Lupin Ltd
- Cocid DSR Capsule manufactured by Talent India
- Praztac-D Capsule SR manufactured by Indoco Remedies Ltd
- Pentalink-D 30 Capsule SR manufactured by Lincoln Pharmaceuticals Ltd
- Padup Capsule SR manufactured by Deys Medical
- GR8 -OD Capsule SR manufactured by Franco-Indian Pharmaceuticals Pvt Ltd
- Pantin D Capsule SR manufactured by Hetero Drugs Ltd
- Gudbie-DSR Capsule manufactured by Akumentis Healthcare Ltd
- Protochek D DSR Capsule manufactured by Ipca Laboratories Ltd
Medicines that should not be taken with Pantop D SR Capsule:
Pantop D SR Capsule may not be consumed with –
- Warfarin
- Tramadol
- Digoxin
- Cisapride
- Methotrexate
- Ketoconazole
- Erythromycin
How to store Pantop D SR?
To store the medicine –
- Keep it in a cool and dry place.
- Do not keep Pantop D SR under direct heat or sunlight.
- Keep Pantop D SR away from the reach of children and pets
- Do not dispose of the medicine by pouring it into the sink or flushing it in the toilet.
FAQs:
1) What is Pantop D SR used to treat?
Ans: Pantop D SR Capsule may be prescribed for the treatment of Gastric motility disorders. The medicine may also be prescribed for the prevention of nausea and vomiting.
2) What are the side effects?
Ans: Some of the side effects associated with consumption of Pantop D SR Capsule are –
- Diarrhea
- Feeling low
- Extrapyramidal symptoms
- Dryness of the mouth
- Constipation
- Increased risk of bone fractures
- Dizziness
- Rashes
- Enlargement of the breasts
- Tenderness in the breasts
3) Is Pantop D SR Capsule safe for pregnant women?
Ans: No. Pantop D SR may not be considered safe for pregnant women. However, the doctor may prescribe the medicine depending upon the clinical condition.
4) Is the consumption of Pantop D SR safe for lactating mothers?
Ans: No. Pantop D SR is not prescribed to lactating mothers. However, if the benefits outweigh the associated risks the medicine may be prescribed.
5) What is the duration of effect for Pantop D SR Capsule?
Ans: Pantop D SR is very effective and its effect may last up to six hours.
6) What is the onset of action of Pantop D SR?
Ans: The effect of Pantop D SR can be observed within 30 – 60 minutes of administering it.
7) Is Pantop D SR Capsule addictive?
Ans: No. Pantop D SR is not habit forming. No such cases have been reported till date.
8) Can Pantop D SR be used to reduce excess acid secretion in the stomach?
Ans: Pantoprazole present in the medicine is a proton pump inhibitor which works by decreasing the production of acid in the stomach. Therefore, the medicine is usually prescribed to treat conditions like GERD in which excess acid is produced in the stomach.
9) How long do patients need to use Pantop D SR Capsule before they observe an improvement in their condition?
Ans: The patients may observe an improvement within a day of consuming Pantop D SR. However, the time may vary from patient to patient.
10) At what frequency do the patients need to use Pantop D SR?
Ans: The most common dosage for Pantop D SR Capsule is one capsule per day. The dosage may vary from patient to patient depending upon their condition.
11) How should Pantop D SR Capsule be consumed?
Ans: Pantop D SR is usually taken empty stomach.
