Lasilactone 50 Tablet is a diuretic drug used for the treatment of edema caused due to chronic cardiac failure, resistant hypertension, and hyperaldosteronism. It is manufactured by Sanofi India Limited.
| Nature | Aldosterone antagonist Diuretic |
| Uses | Edema, Resistant Hypertension, Hepatic cirrhosis, chronic Cardiac Failure |
| Composition | Furosemide (20 mg) and Spironolactone (50 mg) |
| Side effects | Hearing impairment, skin rash, Weakness, Dizziness, Muscle Spasms, Nervousness |
| Precautions | Patients suffering from diabetes, electrolyte imbalance or kidney- related ailments |
Uses and Benifits of Lasilactone Tablet:
This medicine has several uses:
- Lasilactone 50 tablet is used to treat edema, which is the accumulation of fluids in the tissues.
- This medicine is also used for the treatment of resistant hypertension, in which the blood pressure remains high (generally above 140/90 mmHg), in spite of simultaneously using three antihypertensive agents.
- Lasilactone is also used in cases of chronic cardiac failure
- Lasilactone 50 also aids in treating edema that is resistant by nature, especially when associated with hyperaldosteronism.
- This medicine is also used as a treatment of hepatic cirrhosis. A few symptoms associated with this condition are jaundice, swelling of joints and excessive loss of weight.
Side Effects of Lasilactone Tablet:
Lasilactone 50 Tablet is generally deemed safe for use but may cause certain undesirable side effects in some cases. Some of the commonly occurring side effects are listed below:
- Lasilactone tablet affects the levels of certain elements present in the blood. It may lead to low sodium, magnesium, and calcium levels, and increased uric acid. The ingredients of This drug also affect the level of potassium in the blood.
- In men, Lasilactone 50 MG tablet may lead to gynecomastia or breast enlargement.
- In women, Lasilactone tablet may lead to irregular menstruation.
- Other possible side effects include headache, hearing problems, weakness, dizziness, stomach pain, muscle spasms, irregular heart rate, and skin rashes.
- An allergic reaction to This medicine is also possible in patients having a hypersensitivity to the constituents of the medicine.
In case the patient experiences severe or prolonged side effects post administration of Lasilactone tablet, it is advised to consult a doctor immediately to seek remedial action.
Common Dosage of Lasilactone Tablet:
Lasilactone tablet should be taken at the time and frequency prescribed by the doctor. It is advised to take the medicine after having food for maximum efficacy. However, dietary sodium should be avoided during the course of This drug. The tablet must be administered whole, without crushing, breaking or chewing it.
- Missed Dose: In case the patient has missed a dose of Lasilactone 50 tablet, it must be taken as soon as it is remembered. In case it is almost time for the next scheduled dose, it is advised to skip the missed dose and take the next dose at the prescribed time. Under no circumstance should a double dose of the medicine be taken, it may lead to serious side effects.
- Over Dosage: In case of a suspected overdose, it is essential to report the same to the doctor prescribing the medicine, especially on experiencing any side effects; to seek immediate medical assistance.
Composition and Nature of Lasilactone Tablet :
Lasilactone 50 tablet consists of two major ingredients: 20 mg of Furosemide and 50 mg of Spironolactone. Both these ingredients bear diuretic properties. This medicine is an Aldosterone antagonist Diuretic that balances the level of electrolytes and potassium in the body.
Precautions and Warnings – When to Avoid Lasilactone Tablet?
- It is advised not to consume alcohol while administering Lasilactone 50. Consuming alcohol may cause adverse effects such as dizziness, fainting, headaches, or change in the heart rate.
- Pregnant women are advised against the use of this medicine as it may cause harm to the developing fetus. The medicine must only be administered if it is deemed absolutely necessary by a doctor and the benefits outweigh the risks associated with its consumption.
- Patients suffering from kidney related ailments are advised to exercise caution while administering this medicine. The medicine must only be administered post consultation from a doctor. Regular monitoring of the kidney function may be advised by the doctor in such cases.
- Patients suffering from severe liver-related ailments are advised against the use of Lasilactone. If prescribed by a doctor, the medicine can be administered by strictly adhering to the dosage instructions.
- The probability of occurrence of side effects in elderly patients is higher; medicine should be used with extreme caution in such cases.
- Lasilactone is known to cause a change in the level of electrolyte and glucose in the body. Thus, diabetic patients are advised to exercise caution while taking the medicine.
- This medicine is not recommended to be administered to children.
Substitutes of Lasilactone Tablet:
Medicines with the same nature, composition, and course of action can be used as substitutes of the medicine. Some of the commonly available substitutes are:
- Aldoloc 20 mg/ 50 mg tablet manufactured by the Thrift Pharmaceuticals
- Amifru-S Tablet manufactured by the Torrent Pharmaceuticals
- Spiromide tablet manufactured by the RPG Life Sciences Limited
- Fruselac tablet manufactured by the Lupin Limited
- Frusis 20 mg/50 mg Tablet manufactured by theIntel Pharmaceuticals
- Lactomide Tablet manufactured by the S V Biovac Pharmaceuticals Pvt Ltd
- Aldostix 20 mg/50 mg manufactured by the Tablet Bal Pharma Ltd
- Amifru-S Tablet manufactured by the Torrent Pharmaceuticals Ltd
- Urecton Plus 20 mg/50 mg Tablet manufactured by the Depsons Pharma
Lasilactone 50 Tablet Interactions with Other Drugs:
This medicine may interact with certain products, drugs or medical conditions and cause adverse side effects.
Food Interactions
When administering Lasilactone 50 tablet, it is advised to not consume food rich in potassium, as it may worsen the electrolyte balance in the body.
Alcohol Interaction
It is recommended to not consume alcohol while administering Lasilactone as it may cause dizziness, headache and excessive drowsiness in some cases.
Interaction with Disease
Patients suffering from the following medical conditions are advised against the use of Lasilactone 50 mg tablets as it may lead to health complications-
- Diabetes
- Kidney related disorders
- Electrolyte imbalance
Interaction with medicines
It is not recommended to co-administer the following medicines along with This medicine as it may result in severe drug interactions-
- Antidepressants
- Aminoglycoside antibiotics
- Angiotensin-converting enzyme inhibitors (ACEI’s)
- Metformin
- Nonsteroidal anti-inflammatory drugs
Variants of Lasilactone 50 mg Tablet:
Lasilactone tablets have 2 major variants with the same chemical composition in varied amount. They are-
- Lasilactone 50 mg Tablet- It contains 20 mg of Furosemide and 50 mg of Spironolactone.
- Lasilactone 100 mg Tablet- It contains 20 mg of Furosemide and 100 mg of Spironolactone.
Lasilactone Tablet Price in India:
| Name of the medicine | Price (Quantity) |
| Lasilactone tablet | INR 40.29 ( 10 Tablets) |
How Lasilactone 50 Works?
Lasilactone 50 tablet contains two primary ingredients; Furosemide and Spironolactone, both of which are diuretics. Furosemide works by removing excess water and some electrolytes from the body through urine.
Furosemide reduces the level of potassium in the blood and relaxes the blood vessels, whereas spironolactone prevents the loss of potassium. The two medicines work together to balance the level of potassium in the body.
How to use Lasilactone Tablet?
- Lasilactone 50 tablet should be swallowed whole with water. It is not advised to administer the medicine on an empty stomach.
- It is not recommended to crush, break or chew the tablet before consumption.
- This medicine is generally advised to be taken after having a meal for maximum efficacy.
When is Lasilactone Tablet prescribed?
Lasilactone tablet is generally prescribed to treat symptoms associated with the following conditions-
- Chronic cardiac failure
- Hepatic cirrhosis
- Resistant Hypertension
- Resistant edema associated with secondary Hyperaldosteronism
Medicines That Should Not be taken with Lasilactone:
Some medicine, when administered along with Lasilactone 50 mg tablet, may cause the occurrence of severe side effects. Some of these medicines are-
- Antidepressants
- Aminoglycoside antibiotics
- Angiotensin-converting enzyme inhibitors (ACEI’s)
- Metformin
- Nonsteroidal anti-inflammatory drugs
How to Store Lasilactone Tablet?
- Lasilactone tablet must be stored away from direct heat and sunlight.
- It must be stored in a cool and dry place.
- It must ideally be stored between 15°- 30° C
- It must be kept out of reach of children and pets
- The packaging of the medicine must not be tampered with in order to maintain its efficacy on consumption.
FAQs:
1) Is it safe to drive while administering Lasilactone?
Ans: Lasilactone is known to cause symptoms such as dizziness or headaches in a few cases. As such it may not be safe to drive after using Lasilactone tablet.
2) Is it safe to breastfeed while administering Lasilactone?
Ans: Lasilactone is not known to cause any harm to the nursing infant as it does not pass through the breast milk in large amounts. However, it is best to consult with a doctor before starting the dose of the medicine for case-specific recommendations.
3) Can Lasilactone be administered along with antibiotics?
Ans: It is not advisable to administer Lasilactone along with antibiotics as they may cause severe side effects. It is recommended to consult a doctor before co-administering medicines in order to avoid the occurrence of adverse effects.
4) Is Lasilactone safe for use by pregnant females?
Ans: The medicine is not deemed safe for use by pregnant females as it is known to cause an adverse effect on the developing fetus. A doctor must be consulted before starting a dose of this medicine for case-specific recommendations and appropriate dosage instructions.
5) Is Lasilactone Tablet addictive in nature?
Ans: No, Lasilactone Tablet is not addictive in nature. All addictive drugs in India are classified under schedule X or H. It is advised to read the packaging label of the drug carefully for all the related information.
6) Can I stop taking the medicine abruptly if I see an improvement in my condition?
Ans: No, it is not advised to abruptly stop the dosage of the medicine even if an improvement in the condition is noted. A doctor must be consulted before making any changes to the prescribed dosage instructions in order to avoid the occurrence of any side effects.
7) What will happen if I accidentally have an expired dose of Lasilactone Tablet?
Ans: Although it is always recommended to check the expiry date of the medicine before administering it, a single expired dose may not cause any serious side effects. It must be noted that the efficacy of the drug may be hampered as an expired dose will not be as effective in treating the symptoms as well as the unexpired dose. In case of experiencing any side effects, a doctor must be consulted immediately to seek remedial action.
8) I accidentally missed taking a dose of Lasilactone 50 Tablet. What should I do?
Ans: It is generally adviced to take the missed dose as soon as it is remembered. In case it is almost time for the next scheduled dose, it is recommended to administer the next dose and miss the skipped dose. Under no circumstance should a double dose be taken to compensate for the missed dose as it may lead to drug toxicity or other side effects.
9) I have taken a double dose of Lasilactone 50 Tablet. What should I do?
Ans: In case of a suspected overdose, it is advised to consult a doctor to seek remedial action.
10) What is the general recommended dosage of Lasilactone 50?
Ans: The general prescribed dosage advised by the doctor is one tablet per day. The dosage of the medicine may vary from person to person as it depends on the health condition, age, and BMI of the patient. Thus, a doctor must be consulted for appropriate dosage instructions.
11) How much time does a dose of Lasilactone 50 take to show effect?
Ans: The time of onset of action is generally noted to be 30-60 minutes. The patients generally experience an improvement in their condition within an hour of oral administration.
12) Should I administer Lasilactone before or after having a meal?
Ans: It is commonly advised to administer the medicine after having a meal for maximum efficacy. For case-specific recommendations, it is advised to consult a doctor before starting the dose of the medicine.
13) Is Lasilactone available as an Over-the-Counter medicine?
Ans: No, Lasilactone 50 Tablet is a prescription-only medicine that is only available after getting a prescription from a doctor. It cannot be purchased Over- the- Counter.
14) What is the medicine used to treat?
Ans: This medicine is generally used to treat edema or swelling in various body parts caused due to resistant hypertension, hepatic cirrhosis, hyperaldosteronism, and chronic cardiac failure.
15) What are the common side effects associated with Lasilactone?
Ans: The common side effects associated with Lasilactone 50 Tablet are reduced levels of magnesium and calcium, headache, muscle spasms, hearing impairment, skin rashes, irregular heartbeat, and weakness.
16) What is Lasilactone 50 Tablet used for?
Ans: Lasilactone 50 Tablet is generally used for treating edema caused due to an imbalance in the level of electrolytes and potassium in the body. Resistant edema caused due to resistant hypertension, secondary hyperaldosteronism, hepatic cirrhosis, and chronic cardiac failure may also be relieved, treated or prevented by the use of Lasilactone 50 Tablet.
17) Can I take Lasilactone 50 mg Tablet along with antidepressants?
Ans: Antidepressants are not recommended to be administered along with Lasilactone 50 mg Tablets as they are known to cause severe side effects when co-administered. A doctor must be consulted for advice before starting the dose of any medicine to avoid the occurrence of side effects arising out of medication interactions.
18) Can administering Lasilactone cause dehydration?
Ans: Yes, dehydration is a very common side effect associated with the use of Lasilactone 50 Tablet. The use of the medicine causes excessive urination that may result in excessive dehydration. It is recommended to stay hydrated to avoid dehydration.
19) What are the general precautions and warnings to be followed while taking Lasilactone Tablet?
Ans: It is advised to stop the consumption of alcohol during the course of Lasilactone 50 mg. This is because consuming alcohol while administering the medicine may cause adverse side effects such as weakness, drowsiness, dizziness, fainting, headaches, or changes in the heart rate.
- Lasilactone tablet is not recommended to be administered to children.
- Patients suffering from severe liver-related ailments must exercise caution while administering This medicine.
- Patients suffering from kidney related ailments are not advised to administer this medicine. The medicine must only be administered post consultation from a doctor. Regular monitoring of the kidney function may be advised by the doctor in such cases.
- Pregnant women are not advised to use this medicine as it may cause pose a health-related threat to the developing fetus. The medicine must only be administered if it is deemed absolutely necessary by a doctor and if the benefits outweigh the risks.
- Lasilactone is known to cause a change in the level of electrolyte and glucose in the body. Thus, diabetic patients are advised to exercise caution while taking the medicine.
- Elderly patients should exercise extreme caution while using the medicine as the probability of occurrence of side effects in such patients is higher.
20) What are the storage instructions for the medicine?
Ans:
- The medicine should be stored away from direct sunlight and heat.
- It should be stored in a dry and cool place.
- The ideal temperature for storing the medicine is 15°- 30° C
- The medicine should be kept out of reach of pets and children
- The packaging of the medicine must not be tampered with in order to maintain its efficacy on consumption.
