Janumet: Uses, Side Effects, Composition, Dosages & Price

Janumet: Uses, Side Effects, Composition, Dosages  & Price post thumbnail image

Janumet is a medicine that is used to treat Type 2 Diabetes Mellitus. Usually, people who get Diabetes need to suffer from it for a long period of time. By taking proper medication, one can survive for a long time in a healthy manner. In fact, Diabetes mellitus type 2 is a metabolic disorder that is caused due to increased blood sugar and deficiency of insulin. Some of the major symptoms of this disease include enhanced thirst, feeling like the patient needs to urinate in regular intervals of time, and sudden weight reduction. 

Such symptoms can be reduced with the intake of Janumet medicine. This tablet comprises a couple of diabetes medicines such as metformin and sitagliptin. If you are seeking to cure your type 2 diabetes then, you need to use this medicine. Besides this, you need to follow a standard diet plan and exercise regularly to main the sugar levels in the blood. By lowering the sugar levels in the blood, one could cure type 2 diabetes.

Uses & Benefits of Janumet:

As this is a combination medicine, this tablet can be used alongside proper diet and exercise on a regular basis. The patients need to use some other medicines in order to maintain their increased blood sugar. There are abundant benefits of using the Janumet tablet for reducing Type 2 Diabetes. Here are some of the uses of Janumet listed below:

  • Diminishes the Blood glucose levels in the people who are suffering from Type 2 Diabetes

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Side Effects of Janumet:

Whenever you intake this medication, you might come across some of the major and minor side effects. These side effects may or may not be experienced by the patients who are suffering from Type 2 Diabetes. However, these are just the potential side effects that might be affected due to the overdosage. Here, we have compiled a list of the potential side effects that include the following:

  • Nausea
  • Vomiting
  • Diarrhea
  • Changed taste
  • Joint cramps
  • Pain in the Abdomen
  • Diminished Hunger
  • Distress
  • Fever
  • Fatigue
  • Hypoglycemia
  • Constipation
  • A sore throat
  • A dry cough
  • Vision turns blurred
  • A headache
  • Swelling Joints    
  • Runny and stuffy nose
  • No comfort in the chest

All these are some of the possible side effects that might affect the patients who are suffering from Type 2 Diabetes. One who experiences any of the symptoms needs to consult the doctor as soon as possible without any delay. However, the aforementioned side effects can be seen only in a small number of people.

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Common Dosages of Janumet:

The dosage of Janumet depends on the condition and the age of the patient. If you ever missed the dose then, it might become a problem for your health. Once you remember about the medicine, you can consume it if the time doesn’t exceed much. In case, if the time is for your subsequent dose then, you can simply skip the first dose. There must be a gap of at least 5 to 6 hours between the first and second dose. Don’t double your dose if you missed the first one. If in case, the dose becomes over then, you need to contact the doctor immediately.

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Composition and Nature of Janumet:

The composition of Janumet comprises Sitagliptin Phosphate Monohydrate which is equivalent to 50 milligrams of Sitagliptin and 1000 milligrams of Metformin hydrochloride. These are some of the active ingredients present within the Janumet tablet.

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How to Use Janumet?

When the doctor prescribes this medicine for patients who suffer from Type 2 diabetes, the medicine must be taken twice a day. Usually, the doctor prescribes the medicine to be taken after meals. The patients suffering from this disease must and should drink plenty of water and other liquids in order to get rid of this disease. One should not break the medicine prior to consuming it. 

The physician prescribes this medicine depending on the medical conditions and the way you respond to the treatment. Try to maintain your healthy diet plan correctly and exercise on a regular basis. By enduring this meal plan for a certain period of time, you can reduce your blood sugar levels. You need to keep track of your blood sugar on a frequent basis. Discuss your blood sugar levels with your doctor and get the treatment accordingly.

How does Janumet work?

The Janumet tablet is a blend of two active ingredients such as metformin and sitagliptin. One can use this medicine along with consuming the food with a proper diet plan and regular exercise. This medication works by reducing the blood glucose sugar levels in adults suffering from Type 2 diabetes. Sitagliptin is one of the active ingredients of Janumet tablet that belongs to the DPP-4 Inhibitors. The functionality of this ingredient is to enhance the quantity of incretin produced by the intestine. 

In fact, Incretin is a hormone that improves insulin levels whenever the blood sugar levels are increased. It plays a crucial role in maintaining glucose levels within the body. On the other hand, Metformin is another medication that belongs to biguanides. This ingredient has the ability to lessen the glucose levels that are produced by the liver. This, in turn, helps the glucose to penetrate into the body tissues. The Janumet tablet is available in the market with a plethora of brand names.

When Not to Use Janumet?

If you have the following symptoms of allergic conditions, you should not intake this medication: 

  • During breastfeeding
  • Extreme dehydration
  • If allergic to the ingredients such as Metformin and Sitagliptin
  • During pregnancy or while planning to become pregnant
  • When you intake alcohol in massive quantities
  • If you have a history of cardiovascular attack
  • If you have undergone surgery or any kind of infection
  • Suffering from Kidney disease and Liver dysfunctional
  • If you have metabolic acidosis

Warnings and Precautions – When to Avoid Janumet?

Before using this medicine, the patients need to take necessary precautions as given below:

Whenever the dose of Metformin increases in your medication then, it could lead to a complicated condition namely lactic acidosis. It might lead to the final stage of death.

The person who is suffering from Lactic Acidosis then he/she might experience the following symptoms:

  • Fatigue
  • Muscle pain
  • Breathing problem
  • Diarrhea
  • Abnormal heartbeat
  • Lightheadedness
  • Vomiting

In case, the Lactic Acidosis is in the complicated stage then, you might experience the following symptoms:

  • Kidney Diseases
  • Liver Issues
  • Heart Attack

If the intake of Janumet tablet increases then, it might lead to Pancreas disorder. It could sometimes become severe and finally, lead to death in some situations. If you have the following issues already then, discuss the same with your physician:

  • Pancreatitis
  • Increased blood sugar levels
  • Gallbladder stones
  • Consumption of alcohol in heavy quantities

If you are using Janumet along with other medication for curing type 2 diabetes then, it might lead to low blood sugar. Whenever the blood glucose levels in your body fall down then, it leads to hypoglycemia. In such a case, sulfonylurea medicine dosage must be reduced. Whenever you get hypoglycemia then, you might experience the following symptoms:

  • Dizziness
  • Fatigue
  • Appetite
  • A headache
  • Horrible sweating
  • Increased heartbeat

Besides the above-given warnings, there is a serious warning to those who are suffering from kidney problems and diabetes. It is not recommended to use Janumet if you have extreme joint pain.

Substitutes for Janumet:

There are some substitutes for Janumet tablet. The tablets that are listed below have similar compositions, strengths, and forms. 

  • Istamet 50Mg/1000Mg Tablet

Janumet Interactions with Other Drugs:

If you are using the Janumet tablet alongside some other medications then it might show interactions. Here is a list of some medicines that show medicine interactions:

  • Vancomycin
  • Trimethoprim
  • Triamterene
  • Ranitidine
  • Quinine
  • Quinidine
  • Procainamide
  • Morphine
  • Digoxin
  • Amiloride

Due to the risk of drug interactions, you need to face some adverse effects. After discussing your medications with your doctor, he/she will look out for remedies or tell you to stop consuming the medicines.

People who are suffering from vitamin B12 deficiency need to be careful before consuming this medicine. If you intake Janumet along with the Vitamin B12 tablet then, the condition of the patient might become complicated. Tell your doctor about your deficiency problem and take proper medication.


Most people suffering from type 2 diabetes often visit the doctor for checking their sugar levels. Some of them hesitate to ask their doubts and queries regarding their health and the medicines prescribed by the doctor. If you can’t ask them directly, we are here to provide proper assistance through this article. Here are some of the commonly asked questions related to Janumet medicine:

1) Can I Intake Alcohol When Using Janumet?

Ans: If you consume alcohol alongside the Sitagliptin ingredient then, it might show a massive impact on the blood sugar levels in the patients who are suffering from diabetes disease. As metformin is another active ingredient of the Janumet tablets, it shouldn’t be consumed alongside alcohol. Due to the intake of alcohol, it might cause lactic acidosis. Eventually, it causes respiratory issues, discomfort in the heart, stomach pain, and drowsiness.

2) Can I Drive a Vehicle When using Janumet?

Ans: Some of them have experienced drowsiness after using this medicine. Moreover, it could cause Hypoglycemia if you drive a vehicle or operate some heavy machinery.

3) Will this Medicine Show Impact on Kidney Functionality?

Ans: It is not at all recommended for those who are suffering from kidney disease. People having renal disease at a severe stage should not use this medicine. However, it is advised to take a proper suggestion from the doctor prior to using it.

4) Can a Person with Liver Disease intake Janumet Medicine?

Ans: If you have the liver disease at a complicated stage then, you should avoid taking this medicine. Before using this medicine, you need to discuss your liver disease with your doctor.

5) Is it Safe to Use Janumet medicine while breastfeeding?

Ans: It is a danger for women and infants to use Janumet tablets at the time of breastfeeding. As per some studies, this medicine might show some adverse effects on the child. Before using this medicine, try to contact your physician.

6) Can I Use Janumet during pregnancy?

Ans: Some of the women suffer from diabetes when they are pregnant. It might show some side effects on the fetus. Hence, try to explain it to your doctor so that he/she gives proper advice for reducing your blood sugar levels.


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