Drotin Tablet: Uses, Side Effects, Composition, Price & Dosage

Drotin Tablet: Uses, Side Effects, Composition, Price & Dosage post thumbnail image

Manufactured by Walter Bushnell, Drotin tablet is a drug that falls into the category of Anticholinergic/ Antispasmodic drugs. Drotin contains Drotaverine as its primary ingredient to relieve spasms and twitches in the smooth muscles of the stomach and heart. Drotin may also be used to relieve menstrual pain, cervical spasm during labor and pain due to irritable bowel syndrome.

Nature of Drotin:Anticholinergic/ Antispasmodic
Uses of Drotin:Stomach ache, Abdominal cramps, Functional bowel disorders, Pain in renal colic, Menstrual Pain, Labour pain, Pain due to gallstones, Pain due to liver and gallbladder related diseases
Composition of Drotin:Drotaverine
Side Effects of Drotin:Nausea, Vomiting, Headache, Dizziness, Heartburn, Altered pulse rate, Difficulty in breathing, Allergic skin reactions, Low blood pressure, Swelling of face, tongue, hands, and feet
Precautions of Drotin:Hypersensitivity, Liver-related diseases, Renal Diseases, Pregnancy, Breastfeeding, Hypotension

Uses and Benefits of Drotin:

Drotin Tablet is an Antispasmodic drug that is used to treat twitches in the smooth muscles of the stomach and heart. A few conditions for which this tablet is prescribed are:

  • Abdominal Pain
  • Chest Pain
  • Menstrual Pain
  • Bowel Disorder
  • Pain due to liver disease
  • Gallstones Pain in Kidney
  • Pain due to kidney stones
  • Pain due to gastro-intestinal colicky pain
  • Pain in renal colic irritable
  • Cervical spasm during labor

Side Effects of Drotin:

Side effects of Drotin Tablet are rare but can be noticed as the following condition-

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Sweating
  • Sleep Disorder
  • Allergic dermatitis
  • A headache
  • Irregular heart rhythm
  • Fainting
  • Flushing (sense of warmth in the face, ears, neck, and trunk)
  • Decreased blood pressure

There may also be cases of blurred vision and rashes, in which case it is advisable to visit the doctor immediately.

Common Dosage of Drotin:

The patient should administer Drotin Tablet in accordance to the instructions prescribed by the doctor. The dosage may vary with the severity of the ailment it is prescribed to treat. A few other factors that help in deciding the dosage are the BMI of the patient, age of the patient and other underlying health concerns.

  • Missed Dosage: Patients should take the missed dose as soon as it is remembered. However, it is advisable not to take the missed dose if it is almost time for the next dose.
  • Over Dosage: Overdosage may show serious side effects or drug toxicity and thus one should refrain from taking an overdose. However, if an overdose is suspected, one must seek immediate medical attention.

Composition and Nature of Drotin:

Drotin Tablet is a muscle relaxant that belongs to the category of ‘Antispasmodic Drugs’. It contains Drotaverine (40 mg) as its active ingredient. Drotaverine is a selective inhibitor of phosphodiesterase 4.

Drotin Price in India:

VariantPrice (in INR)Quantity
Drotin Tablet54.0110 Tablets
Drotin DS Tablet139.5115 Tablets

How Drotin Tablet works?

Drotin 40 MG Tablet is an anticholinergic that contains Drotaverine as its main ingredient. The tablet works as a muscle relaxant by restoring the balance of cyclic AMP, along with calcium ions at the site of spasm at smooth muscles. This restoration is done by inhibiting PDE4 (Phosphodiesterase-IV) enzyme.

How to Use Drotin?

It always recommended ingesting the tablet whole. The tablet must not be chewed, diluted or crushed. It is best to administer Drotin with water. Even though it can be taken before or after food, it is best to take it at a fixed time for faster effect and increased efficacy.

Drinking alcohol should be avoided during the dosage period. It is advisable for pregnant women to consult their gynecologist regarding consuming this medicine. Also, kidney and liver patients must seek advice from their doctor before consuming this medicine.

When is Drotin Prescribed?

Drotin Tablet is an anticholinergic drug that is primarily used to treat muscle spasms in the stomach and heart. Drotin is prescribed to relieve the pain caused due to irritable bowel syndrome, menstrual cycle, kidney and gallstones, and liver-related disorders. Doctors may also prescribe this medicine to enhance cervical dilation during childbirth.

Warnings and Precautions- When to avoid Drotin?

A few concerns that should be taken into consideration before consuming Drotin 40 mg Tablet are:

  • Renal Impairment : Drotin Tablet shows severe side-effects in patients suffering from renal impairment. It should be used with extra care and caution in patients having a known history of kidney related disorder. Appropriate dose adjustment and close monitoring of kidney function may be required in such cases.
  • Pregnancy : Drotin Tablet might show adverse effects on the fetus. For this reason, the use of this medicine in pregnant women should be avoided unless potential benefits outweigh the risks. One must consult the doctor for case-specific recommendations.
  • Breastfeeding : The risk of adverse effects of this medicine on infants is significantly high when consumed during the lactation period. Hence, the use of this medicine should be avoided by the ladies during their lactation period.
  • Liver Disease : Drotin Tablet shows adverse effects in patients suffering from liver-related ailments.  Hence, it should be used with extra care and caution in patients having a known history of liver related ailments. Appropriate adjustment to the dose and close monitoring of liver function parameters should be taken into account in such cases.
  • Hypotension : Drotin Tablet has been reported to lower down the blood pressure in patients suffering from hypotension.  Hence, the use of this medicine is not advisable for such patients.

A few other points of concern are:

  • Prolonged use of this medicine has indicated habit-forming tendencies, thus patients should not consume this medicine over a long period of time. A doctor must be consulted before discontinuing the usage of this medicine.
  • Any patient with genetic disorders of skin and blood should avoid this tablet, or at least undertake consultation.
  • This tablet should not be consumed if the patient is going to drive, as it may cause vertigo. As an extension, handling of any heavy machinery should also be avoided, as it could lead to accidents.
  • This tablet should be taken prior to meals in order to reduce post-meal symptoms. A doctor must be consulted if severe allergic reactions suddenly occur.
  • Women who are pregnant or trying to get pregnant should also consult their doctor before consuming this tablet.

If any of the following situations are encountered before, during or after dosage, it is advisable to consult a doctor immediately.

  • Blood clots in the body
  • Breathlessness
  • Discoloration of skin on the face or neck
  • Pain and swelling under the skin
  • Irregular heartbeat

Substitutes for Drotin:

Below is the list of a few drugs that have the same strength, composition, and form as that of Drotin Tablet, and hence can be used as its substitute.

  • Baralgan D 40 mg Tablet – by Sanofi India Ltd
  • Doverin 40 mg Tablet – by Intas Pharmaceuticals Ltd
  • Drotikind 40 mg Tablet – by Mankind Pharmaceuticals Ltd
  • Trosper 40 mg Tablet – by Dr Reddys Laboratories Ltd
  • Dvn 40 mg Tablet – by Overseas Healthcare Pvt Ltd
  • Samspas 40 mg Tablet – by Aamorb Pharmaceuticals Pvt Ltd
  • Delcoic 40 mg Tablet – by Kontest Chemicals Ltd
  • Dortsil 40 mg Tablet – by Psycormedis

Drotin Tablet Interactions:

Interactions with drugs:

Mixing two or more medicines may change how the efficacy of one or both the drugs and may increase the risk of occurrence of side-effects. It is essentially advised to avoid interaction of Drotin Tablet with the following drugs:

  • Analgesics
  • Levodopa
  • Benzodiazepines
  • Antimuscarinics

Interaction with alcohol:

It is generally advisable to discontinue the consumption of alcohol during the course of this medicine, in order to avoid the occurrence of any adverse side effects.

Disease Interactions:

Drotin Tablet should not be consumed by patients suffering from:

  • Low Cardiac Output
  • Porphyria

Drotin Variants:

Variants of Drotin are:

  • Drotin Tablet
  • Drotin DS Tablet
  • Drotin Suspension
  • Drotin DS Oral Suspension
  • Drotin Injection 2 ml
  • Drotin 40 mg/2ml Injection
  • Drotin Suspension Sugar-Free

Drotin Suspension:

Drotin is available in both tablet as well as suspension form. The suspension form has 3 variants:

  • Drotin Suspension
  • Drotin DS Oral Suspension
  • Drotin Suspension Sugar-Free

Medicines That Should Not be taken with Drotin Tablet

Taking Drotin Tablet in combination with other over the counter medicines, herbal medicines or vitamin supplements may increase the risk of occurrence of adverse side effects. A few drugs that are known to interact with Drotin Tablet are:

  • Levodopa (Severe)
  • Diclofenac (Moderate)
  • Atropine (Moderate)
  • Diazepam (Moderate)

How to Store Drotin?

It is advisable to store Drotin in a cool and dry place away from direct heat and sunlight. One must keep Drotin away from the reach of children and pets. The packaging of this medicine must be kept intact in order to maintain its effect when being administered.


1) I missed a dose of Drotin, what corrective steps should I take?

Ans: In case of a missed dose, it must be taken immediately. However, if it is already time for the next dose, it is advisable to skip the missed dose and take the next scheduled dose to avoid overdose.

2) I took an extra dose by mistake of Drotin, so what is the corrective step?

Ans: In case of a suspected overdose, it should immediately be reported to the prescribing doctor, especially in case of experiencing any adverse side effects, in order to seek remedial action.

3) Is it safe to consume an expired Drotin Tablet?

Ans: Although it is advisable to not consume an expired medicine, a single dose of the expired medicine is highly unlikely to show any ill effects on the patient. In case of experiencing an ill effect on administering an expired dose, a doctor must be consulted immediately.

4) Can the use of Drotin 10 mg Tablet provide relief from Cold?

Ans: No. Drotin 10 cannot be used to get relief from cold. It is advisable to consult a doctor before consuming the drug to treat any medical condition.

5) Can I use Drotin 40 mg Tablet for relieving toothache?

Ans: No. Drotin 40 mg Tablet does not help in relieving toothache as is mainly used for relieving abdominal pain and discomfort.

6) I am thirty weeks pregnant, and have pain in the upper right abdomen, can I have Drotin Tablet?

Ans: Drotin Tablet is generally not recommended to be administered by pregnant women. It is essential to consult a doctor to review if the benefits of this medicine outweigh the risks associated with its consumption.

7) Is Drotin a narcotic substance or a steroid?

Ans: Drotin is neither a narcotic substance nor a steroid. It is an antispasmodic drug that is used for muscle relaxation, especially in the heart and tubular organs of the gastrointestinal tract.

8) Why is Drotin Tablet prescribed?

Ans: Drotin Tablet is an antispasmodic drug that is prescribed to treat muscle spasms in the abdomen and heart. Drotin is also used to relieve the pain caused due to irritable bowel syndrome, menstrual cycle, kidney stones, gallstones, and liver-related disorders. The tablet also aids in enhancing cervical dilation during childbirth.

9) What are the side-effects of administering Drotin 40 mg Tablet?

Ans: Drotin 40 mg Tablet is a relatively safe medicine that shows no major side effects. A few rare but possible side-effects are:

  • Nausea
  • Vomiting
  • Sweating
  • Dizziness
  • Constipation
  • Sleep Disorder
  • Allergic dermatitis
  • A headache
  • Irregular heart rate
  • Decreased blood pressure

10) Can I stop taking Drotin 40 mg Tablet if my pain is relieved?

Ans: No. You should continue taking Drotin 40 mg Tablet for the specific time for which the doctor has prescribed Drotin.

11) Can I consume alcohol during the course of Drotin 40 mgTablet?

Ans: Though Drotin 40 mg Tablet mg shows no interaction with alcohol, Drotin should never be combined with alcohol as it may increase the risk of occurrence of side effects.

12) Can I take Drotin Tablet on an empty stomach?

Ans: Yes, you may take the Drotin Tablet on an empty stomach. However, for better absorption, it is advisable to consume the drug after having a meal. For case-specific recommendations, one must consult the doctor.

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