Ceftum 500 MG Tablet is an antibiotic that treats the infection by inhibiting the formation of the bacterial cell wall. Ceftum 500 is a second generation cephalosporin anti-bacterial drug used to treat a range of bacterial infections. It comes in the form of tablets and injections. Being a second-generation cephalosporin it has anaerobic coverage. It comes in tablet form for oral administration. Ceftum is manufactured and marketed by Glaxo SmithKline Pharmaceuticals Ltd.
Atypical to second generation cephalosporin antibiotic, Ceftum 500 MG Tablet has the capacity to cross stringent evolved immune mechanism or the blood brain barrier which only selectively lets entities reach the brain.
Uses and Benefits of Ceftum:
Ceftum 500 MG Tablet as an antibacterial is used to treat a range of bacterial infections.
Cefuroxime is used for the treatment of bacterial infections. It is utilised for short-term bacterial infection treatment of the skin, urinary tract, and soft-tissues, blood, and lungs (pneumonia). Ceftum 500 is also used to prevent infections after surgery.
It is susceptible to beta-lactamase, like all other cephalosporin antibiotics. This susceptibility is mitigated by its being a second generation variant.
The advantage of lower susceptibility beta-lactamase, the antibiotic inhibiting bacterial enzyme, Ceftum 500 MG Tablet has a harmful effect on the antibiotic action of specific class of antibiotics including cephalosporins. The drug’s limited susceptibility makes it more effective against strains of bacteria including Haemophilus influenzae, Neisseria gonorrhoea, and Lyme disease causing borrelia category bacteria. Some of the uses of Ceftum 500 MG Tablet are listed below:
- Bacterial infections of the throat, sinus, ear, and nose. This includes Otitis media, respiratory tract infections, and any other infections caused by Streptococci and Staphylococci strains of bacteria.
- Bacterial infections of the skin, including pimples and acne.
- Chest infections.
- Gastrointestinal tract infections including the stomach.
- Some sexually transmitted diseases such as gonorrhoea.
- Some urinary tract infections, such as cervicitis and non-gonococci Urethritis which is an infection of the urethra which may be caused by E.coli, Pseudomonas aeruginosa, or Klebsiella.
- Pneumonia caused by Haemophilus influenzae and Streptococcus pneumoniae.
- Bronchitis, an infection in the lungs caused by Haemophilus influenzae, Streptococcus pneumoniae, and some strains of Mycoplasma pneumoniae.
Side Effects of Ceftum 500:
Many side-effects are possible but will not always happen. Some side-effects may be serious, at least if consistent:
- Abdominal pain, vomiting, and nausea are common side effects of Ceftum 500 MG Tablet.
- Allergic reactions might happen in which case the medicine must be discontinued immediately.
- Diarrhoea is a common side-effect of this and many antibiotics. If it is serious then your doctor may offer additional medicine to counter the side-effect.
- You may also get a mild rash, headaches, joint pain, or nervousness from Ceftum 500 MG Tablet.
- As with all bacterial infections, diarrhoea is a risk. All antibiotic therapy will cause the normal microbes in your large intestine to be affected as well. This may cause growth of Clostridium difficile, a bacterium. Severe diarrhoea caused by the Clostridium may not go away on its own, and can be a serious problem.
- If other severe side-effects such as convulsions occur, consult your physician before taking any action.
Common Dosage of Ceftum 500 MG Tablet:
Take Ceftum 500 MG Tablet in the dose and duration as advised by the doctor. If prescribed in tablet form, swallow it as a whole. Do not chew, crush or break the tablet.
Additionally, Ceftum 500 is to be taken with food and dietary sodium must be avoided while taking Ceftum 500 MG Tablet.
If a dose is missed, then it must be taken as soon as one remembers. However, one must not take a double dose if it is already time for your next dose. This may cause adverse effects on the body.
Composition and Nature of Ceftum 500:
Ceftum 500 contains Cefuroxime as the active ingredient which is the antibacterial ingredient.
Precautions and Warnings – When to Avoid Ceftum 500 MG Tablet?
Abnormal stools with traces of blood or mucus must be brought to the notice of the physician.
Prescribed dose must not be skipped. If inadvertently done, take Ceftum 500 MG Tablet when possible but do not double the dose on that account.
In the event of development of rash, itchy skin, swelling of face and mouth or distressed breathing the physician must be informed.
The treatment must not be discontinued on account of Diarrhoea which may occur as a side effect and any drug for symptomatic relief should be taken only under supervision.
- If you’re on blood thinners, Ceftum 500 mg tablet can interact with your medicines and increase your bleeding tendencies.
- Hepatotoxicity has been recorded in certain cases.
- Treatment with Ceftum must not be abruptly stopped unless expressly advised by the attending physician. If the course of Ceftum 500 is stopped mid-way, antibiotic resistant strain of bacteria are prone to develop.
Substitutes for Ceftum Tablet:
The following are common substitutes for Ceftum Tablet:
- Cefakind 500mg Tablet manufactured by Mankind Pharma Ltd
- Zocef 500mg Tablet manufactured by Alkem Laboratories Ltd
- Oratil 500mg Tablet produced by Macleods Pharmaceuticals Pvt Ltd
- Pulmocef 500mg Tablet produced by Micro Labs Ltd
Ceftum 500 MG Tablet Interaction with Other Drugs:
Certain drugs have been reported to interact with this antibiotic which also includes herbal supplements.
The following medication and conditions may interact with Ceftum 500:
- Cases with renal impairment. Nephrotoxicity is associated with high doses of the drug.
To be used with caution in patients with a history of gastrointestinal diseases, particularly colitis.
- Condition like Diabetes Mellitus must be taken in account while prescribing the drug.
- Caution and monitoring is recommended when these agents are prescribed to patients with hepatic disorders.
Variants of Ceftum 500 mg Tablet:
- Ceftum 125 mg Tablet- Cefuroxime (125 mg)
- Ceftum 250 mg tablet – Cefuroxime (250 mg)
- Ceftum 500mg tablet – Cefuroxime (500 mg)
- Ceftum 125 mg Oral suspension- Cefuroxime (125 mg)
Ceftum 500 Price in India:
Medicine Prince in India
Ceftum-500 mg Tablet 4s INR 379.25
How Ceftum Tablet works?
Ceftum is a bactericidal which means that it annihilates bacteria with mode of action including disruption of the process of formation of the bacterial cell wall, which requires synthesis of the peptidoglycan layer which the drug hampers. Absence of peptidoglycan layer severely compromises the structural integrity of the bacterial cell wall.
How to use Ceftum 500?
- The medicine is available in the form of oral suspension and tablet.
- The tablet form of Ceftum 500 is administered via mouth and should be swallowed with water.
- The dosage should be strictly followed according to the prescription of the doctor.
- Usually, it is advisable to take the medicine by twice a day after food.
- The time gap should be even.
The course of the medicine should be finished entirely, and not left in the middle even if the symptoms disappear.
When Ceftum 500 is prescribed?
Ceftum 500 MG Tablet belongs to the category of antibiotic and is prescribed for following conditions:
- Skin infections
- Ear infections
- Urinary tract infections
- Gynecological infections
Medicine not to be taken with Ceftum:
Below mentioned medicines can cause severe interaction, hence they should not be consumed in parallel with Ceftum 500 MG Tablet.
- Amikacin- Moderate
- Furosemide- Moderate
- Chloramphenicol- Moderate
- Cholera vaccine- Severe
- Ethinyl Estradiol- Moderate
How to Store Ceftum Tablet:
Ceftum 500 MG Tablet should be stored between 15°C to 30°C.
The place of storage should be clean and dry place.
Ceftum 500 should be kept away from the reach of pet and children.
Ceftum should be stored in bathroom or near sink.
Suspension of Ceftum Tablet:
Ceftum 500 MG Tablet is also available in suspension form. It is wide range anti-bacterial syrup and is prescribed for treatment of several bacterial infections.
It helps in treatment of bacterial infections such as ear infections, lung infections, urinary tract infections, Lyme disease, etc.
Ceftum 500 should be used under medical supervision by patients with history of kidney diseases.
Frequently Asked Questions (FAQs):
1) Is Ceftum 500 MG Tablet a variant of penicillin antibiotic?
Ans: No, Ceftum 500 MG Tablet is a cephalosporin antibiotic and not a penicillin drug. However, its therapeutic action is similar to penicillin.
2) Can Ceftum 500 incidentally be a steroid?
Ans: No, Ceftum 500 is not and could not produce effects similar to steroidal molecule.
3) How safe is Ceftum if I have G6PD deficiency?
Ans: Ceftum 500 has been reported causing haemolysis. Ceftum 500 MG Tablet is not known to cause haemolysis in glucose-6-phosphate dehydrogenase deficient subjects. After thorough evaluation, the doctor will recommend the correct medicine.
4) Is Ceftum 500 MG tablet useful in the treatment of all urinary tract infections (UTI)?
Ans: Ceftum 500 MG Tablet is prescribed for treating uncomplicated urinary tract infections (UTI). Its efficacy depends upon the strain of bacteria and its susceptibility to the drug.
5) What if Ceftum 500 is taken with azithromycin?
Ans: Both are antibiotics. They are not reported to have significant interaction.
6) Is it safe to take Ceftum 500 MG Tablet with Paracetamol (acetaminophen)?
Ans: Ceftum 500 MG Tablet is not known to have any clinically meaningful interaction with acetaminophen or Paracetamol.
7) Can the use of Ceftum cause constipation?
Ans: Diarrhoea is typical whereas constipation is atypical to Ceftum 500. Occurrence should be reported to the doctor.
8) Does Ceftum cover staphylococci aureus?
Ans: Yes, Ceftum is active against staphylococcus strains. The bacteria are notorious though for developing restrain. Efficacy would depend on duration and susceptibility of infection. Culture would determine that.
9) Can I take alprazolam with Ceftum?
Ans: No drug interactions have been reported with Ceftum 500 MG Tablet. However, interactions cannot be ruled out. Please consult your doctor before taking the two medicines together. Benzodiazepines cannot be stopped abruptly as that may cause withdrawal symptoms.
10) Is it alright to consume Ceftum 500 along with other medicines?
Ans: Ceftum 500 should not be consumed along with antacids, as antacids tend to decrease the effectiveness of antibiotic.
A doctor should be consulted before doing so, if required.
11) What is Ceftum 500 MG Tablet?
Ans: Ceftum 500 MG Tablet belongs to the category of semi-synthetic cephalosporin antibiotic. Ceftum 500 is helpful in relieving several infections including ear, lungs, throat, skin and urinary tract.
12) Is Ceftum 500 safe to be consumed by pregnant women?
Ans: According to research, Ceftum 500 is safe to be consumed by pregnant women in any trimester. However, it is advisable to consume Ceftum 500 MG Tablet after consulting a doctor.
13) How the medicine should be stored?
Ans: Ceftum 500 MG Tablet should be stored between 15-30°C. The place of storage should be dry and away from exposure of direct heat and light.
14) When should the use of Ceftum be avoided?
Ans: Ceftum should be avoided in following conditions:
- If patient is allergic to any ingredient of Ceftum 500.
- If patient has history of kidney disease.
- If patient has history or is currently suffering with seizure disorders, liver impairment and gastrointestinal disorders.