Biluma Cream: Uses, Side Effects, Composition & Dosages

Biluma Cream: Uses, Side Effects, Composition & Dosages post thumbnail image

Biluma cream is an ointment that is mainly used to treat skin-related ailments such as pigmentation, dark spots caused due to pigmentation, and skin discoloration associated with cuts, wounds, tanning, skin trauma, pregnancy, and use of birth control pills. It is also used to reduce the level of melanin in the area to which it is applied. It is manufactured in India by Galderma India Pvt. Ltd.

Nature                                  Skin-whitening cream
Composition      Arbutin, Kojic Acid Dipalmitate, Mulberry extracts, Liquorice, Artocarpus extract, Tetrohydrocurcumin, and Tocopherol or Vitamin E
UsesSkin whitening, treating dark spots like age spots, freckles, and skin discoloration associated with pregnancy, and use of birth control pills.
Side Effects              Redness and itching on the skin surface, skin irritation, and burning.
PrecautionsAvoid using this cream during pregnancy and lactation 

Uses and Benefits of Biluma Cream:

The Biluma cream is used to treat the following apart from contributing to skin whitening:

  • Melasma
  • Acne vulgaris
  • Pruritic manifestations of corticosteroid-responsive dermatoses
  • Inflammatory manifestations of corticosteroid-responsive dermatoses
  • Dermatitis of the scalp
  • Age Spots
  • Skin trauma

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Side Effects of Biluma Cream:

Using Biluma cream rarely causes adverse side effects. Depending on the condition, age, and medical history of the patient, the following side effects may occur:

  • Redness, itchiness, burning sensation and irritation on the area where this medicine is applied.
  • Prolonged use of it may cause thinning and early aging of the skin.
  • Skin inflammation

In case any side effects are observed post-application of the cream, it is important to consult a doctor immediately to seek remedial action.

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Common Dosage of Biluma Cream:

It is important to inform the doctor about any pre-existing illness, allergy, or ongoing medicines so that an appropriate dosage can be prescribed based on the person’s medical condition.

Generally, Biluma cream is recommended to be applied to the affected area twice daily. 

Doctors usually prescribe to continue the use of the cream for at least 6 to 8 weeks to ascertain the best results.

  • Missed Dose : In case a dose of this Cream is missed, it is advised to apply the missed dose as soon as it is remembered. In case the dose is remembered when it is almost time for the next dose, one should skip double application at small intervals.
  • Overdose : In case the patient has applied the ointment in more than the prescribed quantity or at small intervals, it is important to consult the doctor immediately to prevent possible side effects and discomfort arising out of over absorption.

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Composition and Nature of Biluma Cream:

Biluma cream contains six key ingredients:

  • Kojic Acid Dipalmitate
  • Arbutin
  • Liquorice
  • Mulberry extract
  • Tetrahydrocurcumin
  • Artocarpus

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Warnings and Precautions – When to Avoid It?

  • Before starting the Biluma cream treatment, it is important to inform the doctor about the on-going medicines, over the counter drugs, herbal or vitamin supplements, etc.
  • Pre-existing medical conditions, upcoming surgery, and pregnancy should also be brought to the doctor’s notice.
  • The person applying the cream is advised to wash their hands and be careful while using the cream in areas that are sun-burnt, scratched or chapped.
  • The area, to which the this cream is being applied, should be washed and dried before application of the ointment.
  • The quantity of Biluma cream being applied should be in adherence to the doctor’s prescription. A thin layer of this medicine should be applied on the face and be allowed to settle and get absorbed properly.
  • People suffering from hypersensitivity are advised to avoid the use of Biluma cream. The patient is advised to avoid exposure to sunlight and prevent tanning during the course of it.
  • Using a moisturizer along with this ointment is not advisable. A gap of at least 30 minutes should be maintained between the applications.
  • Pregnancy: It may be unsafe to use during pregnancy as it may cause adverse effects on the fetus. Unless deemed absolutely necessary for use by a doctor, it is not advised for pregnant females to administer this ointment.
  • Lactation: It is regarded as unsafe to use by lactating females as the cream may cause toxicity or other side effects in the nursing infant.

It is important to keep the doctor informed about any reactions of the cream.

Substitutes of Biluma Cream:

There are many Biluma products in the market which have the same strength, composition, and form. The following are some of the substitutes of this medicine:

  • Apulex Cream 15 gm manufactured by the Menarini India private limited
  • Melalumin Cream 15 gm manufactured by the Menarini India private limited
  • Cutiyt Total Cream 15 gm manufactured by the Ipca
  • Eyebliss Under Eye Cream 15 gm manufactured by the Intas pharmaceuticals ltd.
  • Depiwhite Cream 15 ml manufactured by the Wockhardt limited
  • Lumivoid Cream 15 gm manufactured by the Torrent pharmaceuticals ltd
  • Depiwhite Advanced Depigmenting Cream 15 ml manufactured by the Wockhardt limited
  • Wunder Eye Advance 15 gm Cream manufactured by the Glenmark pharmaceuticals ltd.

Biluma Cream Price in India

Name of the medicine       Price
Biluma cream (15gm)INR 437

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How does Biluma Cream work?

  • Kojic Acid Dipalmitate is an enzyme that inhibits the synthesis of melanin in the skin. Due to a reduction in the level of melanin pigment, the skin becomes visibly lighter and brighter.
  • Arbutin is natural glycosylated hydroquinone that is derived from berries. It is commonly used for skin whitening and getting rid of skin pigmentation.
  • Tocopherol or Vitamin E bears anti-oxidant properties. It helps in repairing the damaged skin cells as well as lightening of the skin.
  • Mulberry extracts are naturally obtained from the plant Morus alba. They also bear skin lightening properties.
  • Liquorice contains glabridin that is known to prevent pigmentation caused due to UVB rays. It bears anti-inflammatory properties.
  • Tetrohydrocurcumin is a natural ingredient derived from turmeric. It helps in and helps in fading of dark skin.
  • Artocarpus extract is a potent skin lightener having antioxidant properties.

How to Use Biluma Cream?

It is applied topically on the affected area in accordance with the dose and duration advised by the doctor. It is recommended to clean and dry the affected area and then apply the cream. 

During the use of Biluma cream, it is advised to:

  • Avoid contact of the ointment with eyes, nose or mouth.
  • Avoid prolonged sun exposure and sunlamps.
  • Avoid any contact with the affected skin area for at least 15 minutes after applying the ointment.
  • Keep a gap of at least 30 minutes between applying the ointment and moisturizer.

When is Biluma Cream Prescribed?

Biluma cream is an ointment containing natural and artificial skin lightening agents. It is majorly used for skin whitening, lightening, and treating pigmentation and tanning. It is also used to treat dark spots, wound and cut scars, and other skin discoloration associated with skin trauma, pregnancy, and the use of birth control pills.

How to Store Biluma Cream?

  • It is advisable to store the cream in a cool and dry place away from direct heat and sunlight.
  • One is advised to keep the cream away from the reach of children and pets.
  • The packaging of the Biluma cream must be kept intact in order to maintain its effect when being administered.


1) What are the effects of Biluma cream when used for a long period of time?

Ans: Biluma cream contains natural as well as artificial skin whitening agents. It also contains parabens. If used over a long period of time, these medicines can cause the skin to become thin, sinewy, and age faster. People with sensitive skin may experience severe allergic reactions and irritation during prolonged use.

2) Are there any natural alternatives to Biluma cream?

Ans: Yes, there are natural products that mimic the functions of skin-lightening cream. Although Biluma cream is Hydroquinone-free, it does contain certain artificial components such as Kojic Acid Dipalmitate and synthetic Arbutin which may cause irritation and allergic reactions in some cases. 

A few natural alternatives for skin lightening are-

  • Bearberry leaf extract can be used as a skin-lightening product. This extract is known to reduce the production of melanin in the skin. It is rich in a component known as arbutin that aids in clearing up the skin freckles, scars, and discolored patches.
  • Licorice root extract has anti-inflammatory properties. It is a natural product that is readily available in the market in various forms. It helps in controlling oil secretion as well as lightening of the skin.
  • Lemon is another natural product bearing skin-lightening properties. It contains Alpha Hydroxy Acids and Vitamin C.

3) How long does it take for Biluma cream to show its effect?

Ans: The time is taken by Biluma Cream to show its effect depends on the severity and symptoms of the condition for which it is being prescribed. In general cases, one can see positive results within 30 days of continuously using the Biluma cream. 

4) Does this medicine contain steroids?

Ans: No, Biluma cream does not contain steroids. It is a skin lightening cream that contains natural as well as artificial skin lightening agents.

5) What is Biluma cream used to treat?

Ans: Biluma cream is used for skin whitening, pigmentation, and skin lightening. It is also used for treating hyperpigmentation, pimple spots, Melasma, pimple marks, cut marks, and boils on the skin. It is also known to be effective in visibly reducing dark circles and, dark knees and elbows.

6) What are the side effects of Biluma cream?

Ans: Prolonged use of Biluma cream or allergic reactions to one or all of its ingredients may cause the following side effects:

  • Burning of skin
  • Itching
  • Skin rashes
  • Inflammation of skin
  • Skin irritation
  • Early aging
  • Red itchy bumps

It is advised to consult a doctor in case any side effects are experienced to seek immediate remedial action.

7) Does Biluma make scars disappear?

Ans: Biluma cream has is known to bear natural as well as artificial skin lightening and skin whitening. It helps to visibly brighten the skin which in turn may make the scars less noticeable. However, it is not known to completely eradicate the scars on the skin. A doctor must be consulted before using this cream for case-specific recommendations. 

8) How many times in a day should this Cream be used?

Ans: Biluma Cream is generally prescribed to be applied 2 times daily for maximum efficacy. The dosage may vary from patient to patient as the most appropriate dosage is based on- 

  • Age of the patient
  • Condition being treated
  • The severity of the condition
  • Medical history of the patient
  • The weight of the patient

9) I have excessively dry skin. Can I use a moisturizer while using Biluma cream?

Ans: It is generally advised to keep a gap of at least 30 minutes between applying a moisturizing and Biluma Cream. This is because the application of the moisturizer along with the cream affects the absorption of the drug and may interfere with its effectiveness. 

10) Is this Cream addictive by nature?

Ans: Biluma Cream is not known to bear any habit-forming tendencies and thus is not addictive by nature. Medicines that are addictive by nature are characterized as schedule H or X in India and schedule II-V in the US. It is advised to check the label of the medicine for related information. 

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